Researchers Analyzed Space-Grown Crops Microbial Health

A 2022 analysis confirmed that lettuce and wheat grown via aerosol misting on the ISS reached Earth-comparable safety standards.

Updated on Sept. 23, 2026 in Botany

A close-up of green plant sprouts growing within a clear acrylic chamber in a sterile, metallic laboratory environment.
Researchers confirmed that wheat and lettuce grown via aerosol misting on the International Space Station reached Earth-comparable microbial safety standards during a 2022 analysis. AI Illustration. Upload story photo >

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Between June and October 2022, researchers studied crops grown in the XROOTS system on the International Space Station, identifying the microbial makeup of space-raised plants. The study confirmed that foodborne pathogens were absent, establishing a safety baseline for future lunar and Martian missions.

Why it matters

Reducing cargo mass by eliminating traditional soil media is essential for long-term space exploration, and this study provides the first evidence that soil-free systems maintain safe microbial levels. Understanding these plant-microbe relationships is a prerequisite for creating reliable, self-sustaining food production systems for missions to the Moon and Mars.

Researchers identified 65 unique bacterial genera in leaf tissue and 87 in root tissue, with nutrient solution counts ranging from 65 to 3,800 colony-forming units per milliliter. Genetic sequencing of the 16S rRNA gene confirmed that microbial diversity was lower in leaf tissue than in root tissue.

The players

International Space Station

A modular space station serving as a microgravity laboratory for testing human-rated agricultural technology.

The details

The XROOTS system utilized aerosol misting and nutrient-solution flow to deliver water directly to plant roots, bypassing the need for soil. Researchers performed genetic sequencing on the 16S rRNA gene—a ribosomal gene used to identify and classify bacteria—to characterize the microbes present. While the study found fungi such as Fusarium and Blumeria graminis, it observed no visible disease in the lettuce, mustard, wheat, radish, tomato, or pea plants.

Timeline

  1. February 2022: The XROOTS system launched to the ISS.

  2. June 2022 to October 2022: Researchers conducted four plant growouts.

  3. 2017-2018: Earlier Veggie system growouts were conducted on the ISS.

The Tech Race

This research follows the progress established by the Veggie plant growth system on the ISS. It marks a critical step forward in moving from basic vegetable production to verified, food-safe agriculture for long-duration deep space missions.

This development validates the feasibility of soil-free hydroponic systems for future space crews who will depend on autonomous food production. These methods will eventually inform specialized indoor farming technologies for extreme environments on Earth that require high water efficiency and zero-soil substrates.

The takeaway

The successful cultivation of healthy crops in a soil-free, aerosol-based environment demonstrates that microbial safety is achievable in microgravity. Watch for future findings regarding the long-term nutritional composition of these crops, as researchers aim to scale these systems for crewed lunar missions.

Further reading

For more on the evolution of space-based agriculture, see our research in Botany.

Source note: This article includes information reported by The Times of India.

Live Poll

Do you trust the safety of food grown in space for future long-duration human missions?

Researchers Analyzed Space-Grown Crops Microbial Health